Jesseba Fernando

Network Science Institute @ Northeastern University.

about me

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I’m Jesseba, a Network Science PhD student at Northeastern University. I’m advised by Dr. Sam Scarpino. I study how learning alters networks in both the brain and machines, and for this I make use of methods from network science and information theory.

In the brain I study how the functional roles of neurons change as animals learn and relearn, and also how these changes can predict future behaviour. With respect to transformers I look at the representations as they progress layer by layer through the residual stream, investigating how the dynamics of these computations are related to the network’s structure. Composition links them together since both kinds of systems achieve generalisation by recombining what they already know. This flexibility comes at a cost because a system that is able to compose freely loses its ability to tell the inputs apart. I am interested in finding out where this trade-off lies and what causes it.

Before joining Northeastern, I spent five years in Mark Andermann’s lab at Harvard Medical School, studying how hunger and other motivational states change what visual cortex responds to. I then worked with Bill Lotter at Dana-Farber Cancer Institute on how medical imaging models behave when the data they receive differs statistically from the data they were trained on.

In my free time, I co-write Of Two Minds, a newsletter with Grigori Guitchounts.

When I travel I bring more camera than I need, usually to places with bad roads. Some of it ends up here.

news

Jun 12, 2026 Session chair for the neural theory session at Seventh International Conference on Mathematics of Neuroscience and AI.
Mar 16, 2026 Co-organizing the CoSyNe 2026 workshop on Renormalization Principles in Neural Systems with Andrea Santoro and Giovanni Petri.
Jan 16, 2026 Awarded the AccelNet-MultiNet Fellowship. Collaborating with Giovanni Petri, Andrea Brovelli, and Alain Barrat on neural dynamics in Marseille and London this summer.

publications

2026

  1. Bound by semanticity: universal laws governing the generalization-identification tradeoff
    Marco Nurisso, Jesseba Fernando, Raj Deshpande, Alan Perotti, Raja Marjieh, Steven M. Frankland, and 6 more authors
    International Conference on Learning Representations, 2026
  2. Dynamics of the Transformer Residual Stream: Coupling Spectral Geometry to Network Topology
    Jesseba Fernando, and Grigori Guitchounts
    Neural Information Processing Systems, 2026

2025

  1. Transformer Dynamics: A neuroscientific approach to interpretability of large language models
    Jesseba Fernando, and Grigori Guitchounts
    arXiv preprint, 2025

2024

  1. Cortical reactivations predict future sensory responses
    Nghia D Nguyen, Andrew Lutas, Oren Amsalem, Jesseba Fernando, Andy Young-Eon Ahn, Richard Hakim, and 5 more authors
    Nature, 2024
  2. Beyond Structured Attributes: Image-Based Predictive Trends for Chest X-Ray Classification
    Katharina V Hoebel†, Jesseba Fernando†, and William Lotter
    Proceedings of Machine Learning Research Volume 250:610–640 , 2024

2023

  1. Brainstem serotonin neurons selectively gate retinal information flow to thalamus
    Jasmine DS Reggiani, Qiufen Jiang, Melanie Barbini, Andrew Lutas, Liang Liang, Jesseba Fernando, and 5 more authors
    Neuron, 2023

2022

  1. Visual association cortex links cues with conjunctions of reward and locomotor contexts
    Kelly L McGuire, Oren Amsalem, Arthur U Sugden, Rohan N Ramesh, Jesseba Fernando, Christian R Burgess, and 1 more author
    Current Biology, 2022